Cargando…
The Yin and Yang of tRNA: proper binding of acceptor end determines the catalytic balance of editing and aminoacylation
Faithful translation of the genetic code depends on accurate coupling of amino acids with cognate transfer RNAs (tRNAs) catalyzed by aminoacyl-tRNA synthetases. The fidelity of leucyl-tRNA synthetase (LeuRS) depends mainly on proofreading at the pre- and post-transfer levels. During the catalytic cy...
Autores principales: | Tan, Min, Wang, Meng, Zhou, Xiao-Long, Yan, Wei, Eriani, Gilbert, Wang, En-Duo |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3664829/ https://www.ncbi.nlm.nih.gov/pubmed/23585282 http://dx.doi.org/10.1093/nar/gkt252 |
Ejemplares similares
-
Recognition of tRNA(Leu) by Aquifex aeolicus leucyl-tRNA synthetase during the aminoacylation and editing steps
por: Yao, Peng, et al.
Publicado: (2008) -
In vivo identification of essential nucleotides in tRNA(Leu) to its functions by using a constructed yeast tRNA(Leu) knockout strain
por: Huang, Qian, et al.
Publicado: (2012) -
Leucine-specific domain modulates the aminoacylation and proofreading functional cycle of bacterial leucyl-tRNA synthetase
por: Yan, Wei, et al.
Publicado: (2013) -
The tRNA identity landscape for aminoacylation and beyond
por: Giegé, Richard, et al.
Publicado: (2023) -
Low modularity of aminoacyl-tRNA substrates in polymerization by the ribosome
por: Forster, Anthony C.
Publicado: (2009)