Structure of the Catalytic Region of DNA Ligase IV in Complex with an Artemis Fragment Sheds Light on Double-Strand Break Repair

Nonhomologous end joining (NHEJ) is central to the repair of double-stranded DNA breaks throughout the cell cycle and plays roles in the development of the immune system. Although three-dimensional structures of most components of NHEJ have been defined, those of the catalytic region of DNA ligase I...

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Detalles Bibliográficos
Autores principales: Ochi, Takashi, Gu, Xiaolong, Blundell, Tom L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2013
Materias:
Short Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3664939/
https://www.ncbi.nlm.nih.gov/pubmed/23523427
http://dx.doi.org/10.1016/j.str.2013.02.014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3664939/
https://www.ncbi.nlm.nih.gov/pubmed/23523427
http://dx.doi.org/10.1016/j.str.2013.02.014

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