The Molecular Basis of NOD2 Susceptibility Mutations in Crohn's Disease

Nod2 is a member of the NLR family of proteins that initiate inflammatory responses when exposed to ligands derived from bacterial components that gain access to the intra-cellular milieu. It is thus somewhat paradoxical that polymorphisms in the gene that encode NOD2 (CARD15) that lead to impaired...

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Detalles Bibliográficos
Autores principales: Strober, Warren, Kitani, Atsushi, Fuss, Ivan, Asano, Naoki, Watanabe, Tomohiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2008
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3665012/
https://www.ncbi.nlm.nih.gov/pubmed/19079230
http://dx.doi.org/10.1038/mi.2008.42

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3665012/
https://www.ncbi.nlm.nih.gov/pubmed/19079230
http://dx.doi.org/10.1038/mi.2008.42

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