The Phage Lytic Proteins from the Staphylococcus aureus Bacteriophage vB_SauS-phiIPLA88 Display Multiple Active Catalytic Domains and Do Not Trigger Staphylococcal Resistance

The increase in antibiotic resistance world-wide revitalized the interest in the use of phage lysins to combat pathogenic bacteria. In this work, we analyzed the specific cleavage sites on the staphylococcal peptidoglycan produced by three phage lytic proteins. The investigated cell wall lytic enzym...

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Detalles Bibliográficos
Autores principales: Rodríguez-Rubio, Lorena, Martínez, Beatriz, Rodríguez, Ana, Donovan, David M., Götz, Friedrich, García, Pilar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3665550/
https://www.ncbi.nlm.nih.gov/pubmed/23724076
http://dx.doi.org/10.1371/journal.pone.0064671

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3665550/
https://www.ncbi.nlm.nih.gov/pubmed/23724076
http://dx.doi.org/10.1371/journal.pone.0064671

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