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Profile of erlotinib and its potential in the treatment of advanced ovarian carcinoma
The epidermal growth-factor receptor (EGFR) is overexpressed in the majority of epithelial ovarian cancers and promotes cell proliferation, migration and invasion, and angiogenesis, as well as resistance to apoptosis. This makes EGFR an attractive therapeutic target in this disease. A number of stra...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Dove Medical Press
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3665572/ https://www.ncbi.nlm.nih.gov/pubmed/23723710 http://dx.doi.org/10.2147/OTT.S30373 |