Genome-wide identification of transcriptional targets of RORA reveals direct regulation of multiple genes associated with autism spectrum disorder

BACKGROUND: We have recently identified the nuclear hormone receptor RORA (retinoic acid-related orphan receptor-alpha) as a novel candidate gene for autism spectrum disorder (ASD). Our independent cohort studies have consistently demonstrated the reduction of RORA transcript and/or protein levels i...

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Detalles Bibliográficos
Autores principales: Sarachana, Tewarit, Hu, Valerie W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3665583/
https://www.ncbi.nlm.nih.gov/pubmed/23697635
http://dx.doi.org/10.1186/2040-2392-4-14

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3665583/
https://www.ncbi.nlm.nih.gov/pubmed/23697635
http://dx.doi.org/10.1186/2040-2392-4-14

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