Alternative Sigma Factor Over-Expression Enables Heterologous Expression of a Type II Polyketide Biosynthetic Pathway in Escherichia coli

BACKGROUND: Heterologous expression of bacterial biosynthetic gene clusters is currently an indispensable tool for characterizing biosynthetic pathways. Development of an effective, general heterologous expression system that can be applied to bioprospecting from metagenomic DNA will enable the disc...

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Detalles Bibliográficos
Autores principales: Stevens, David Cole, Conway, Kyle R., Pearce, Nelson, Villegas-Peñaranda, Luis Roberto, Garza, Anthony G., Boddy, Christopher N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3665592/
https://www.ncbi.nlm.nih.gov/pubmed/23724102
http://dx.doi.org/10.1371/journal.pone.0064858

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3665592/
https://www.ncbi.nlm.nih.gov/pubmed/23724102
http://dx.doi.org/10.1371/journal.pone.0064858

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