Beta(2)-Adrenoceptor Stimulation Suppresses TLR9-Dependent IFNA1 Secretion in Human Peripheral Blood Mononuclear Cells

INTRODUCTION: IFNA1 (interferon alpha) is a key cytokine regulating the activity of numerous immune cells. Plasmacytoid dendritic cells (pDCs) as natural interferon-producing cells play critical roles as sensors of pathogens and link innate to adaptive immunity. CpG motifs within DNA sequences activ...

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Detalles Bibliográficos
Autores principales: Hilbert, Tobias, Bongartz, Josef, Weisheit, Christina, Knüfermann, Pascal, Baumgarten, Georg, Hoeft, Andreas, Poth, Jens M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3665595/
https://www.ncbi.nlm.nih.gov/pubmed/23724117
http://dx.doi.org/10.1371/journal.pone.0065024

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3665595/
https://www.ncbi.nlm.nih.gov/pubmed/23724117
http://dx.doi.org/10.1371/journal.pone.0065024

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