Cargando…

Beta(2)-Adrenoceptor Stimulation Suppresses TLR9-Dependent IFNA1 Secretion in Human Peripheral Blood Mononuclear Cells

INTRODUCTION: IFNA1 (interferon alpha) is a key cytokine regulating the activity of numerous immune cells. Plasmacytoid dendritic cells (pDCs) as natural interferon-producing cells play critical roles as sensors of pathogens and link innate to adaptive immunity. CpG motifs within DNA sequences activ...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hilbert, Tobias, Bongartz, Josef, Weisheit, Christina, Knüfermann, Pascal, Baumgarten, Georg, Hoeft, Andreas, Poth, Jens M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3665595/ https://www.ncbi.nlm.nih.gov/pubmed/23724117 http://dx.doi.org/10.1371/journal.pone.0065024

Ejemplares similares

Synergistic Stimulation with Different TLR7 Ligands Modulates Gene Expression Patterns in the Human Plasmacytoid Dendritic Cell Line CAL-1
por: Hilbert, Tobias, et al.
Publicado: (2015)

Exome sequencing identifies novel compound heterozygous IFNA4 and IFNA10 mutations as a cause of impaired function in Crohn’s disease patients
por: Xiao, Chuan-Xing, et al.
Publicado: (2015)

Infectious pancreatic necrosis virus proteins VP2, VP3, VP4 and VP5 antagonize IFNa1 promoter activation while VP1 induces IFNa1
por: Lauksund, Silje, et al.
Publicado: (2015)

Beta-Adrenoceptor Blocking Drugs and the Elderly
por: Wilkins, M. R., et al.
Publicado: (1984)

Uses of Beta-Adrenoceptor Blocking Drugs
por: Prichard, B. N. C., et al.
Publicado: (1976)

Synthetic CpG oligonucleotides induce a genetic profile ameliorating murine myocardial I/R injury
por: Hilbert, Tobias, et al.
Publicado: (2018)

β(2) Adrenoceptors are underexpressed in peripheral blood mononuclear cells and associated with a better metabolic profile in central obesity
por: Leite, Fernanda, et al.
Publicado: (2017)

Ly6C(low) and Not Ly6C(high) Macrophages Accumulate First in the Heart in a Model of Murine Pressure-Overload
por: Weisheit, Christina, et al.
Publicado: (2014)

Slow Release Beta Adrenoceptor Blocking Drugs
por: Harron, D. W. G., et al.
Publicado: (1983)

Treatment of Hypertension with Beta-Adrenoceptor Blocking Drugs
por: Bai, Tony R., et al.
Publicado: (1982)

Are Selective Beta-Adrenoceptor Blocking Drugs an Advantage?
por: Kendall, M.J.
Publicado: (1981)

Interaction of miR-181b and IFNA1 Polymorphisms on the Risk of Systemic Lupus Erythematosus
por: He, Yong-Ling, et al.
Publicado: (2020)

TLR-9, but not TLR-2, TLR-3 and TLR-4, is upregulated on peripheral blood mononuclear cells of patients with active systemic lupus erythematosus
por: Papadimitraki, ED, et al.
Publicado: (2005)

Linezolid, vancomycin and daptomycin modulate cytokine production, Toll-like receptors and phagocytosis in a human in vitro model of sepsis
por: Bode, Christian, et al.
Publicado: (2015)

Association of IFNA16 and TNFRSF19 Polymorphisms with Intramuscular Fat Content and Fatty Acid Composition in Pigs
por: Mekchay, Supamit, et al.
Publicado: (2022)

Structural and Functional Analyses of Type I IFNa Shed Light Into Its Interaction With Multiple Receptors in Fish
por: Wang, Zixuan, et al.
Publicado: (2022)

Cytokine pathway variants modulate platelet production: IFNA16 is a thrombocytosis susceptibility locus in humans
por: Gnatenko, Dmitri V., et al.
Publicado: (2022)

Influence of a Single Deuterium Substitution for Protium on the Frequency Generation of Different-Size Bubbles in IFNA17
por: Basov, Alexandr, et al.
Publicado: (2023)

Endothelial permeability following coronary artery bypass grafting: an observational study on the possible role of angiopoietin imbalance
por: Hilbert, Tobias, et al.
Publicado: (2016)

Effects of Separate and Concomitant TLR-2 and TLR-4 Activation in Peripheral Blood Mononuclear Cells of Newborn and Adult Horses
por: Vendrig, Johannes Cornelis, et al.
Publicado: (2013)

TLR2 stimulation induces cardiac inflammation but not cardiac depression in vivo
por: Boehm, Olaf, et al.
Publicado: (2013)

Atopy affects LPS responsiveness and TLR-4 expression in children peripheral mononuclear cells
por: Préfontaine, D, et al.
Publicado: (2010)

Roles of Beta2- and Beta3-Adrenoceptor Polymorphisms in Hypertension and Metabolic Syndrome
por: Masuo, Kazuko
Publicado: (2010)

Tlr4 Deficiency Protects against Cardiac Pressure Overload Induced Hyperinflammation
por: Ehrentraut, Heidi, et al.
Publicado: (2015)

Cytokine Secretion of Peripheral Blood Mononuclear Cells by Hydnocarpus anthelminthicus Seeds
por: Leelawat, Surang, et al.
Publicado: (2018)

Elevated IFNA1 and suppressed IL12p40 associated with persistent hyperinflammation in COVID-19 pneumonia
por: Jeon, Kyeongseok, et al.
Publicado: (2023)

Total Beta-Adrenoceptor Knockout Slows Conduction and Reduces Inducible Arrhythmias in the Mouse Heart
por: Stöckigt, Florian, et al.
Publicado: (2012)

Clinical significance of TLR3 and TLR4 in peripheral blood mononuclear cells from children with Henoch-Schönlein purpura nephritis
por: CHANG, HONG, et al.
Publicado: (2014)

Beta-adrenoceptor regulates miRNA expression in rat heart
por: Hou, Yunlong, et al.
Publicado: (2012)

Increased Beta2-Adrenoceptors in Doxorubicin-Induced Cardiomyopathy in Rat
por: Merlet, Nolwenn, et al.
Publicado: (2013)

Difference between beta1-adrenoceptor autoantibodies of human and animal origin—Limitations detecting beta1-adrenoceptor autoantibodies using peptide based ELISA technology
por: Wenzel, Katrin, et al.
Publicado: (2018)

Evaluating the effect of TLR4-overexpressing on the transcriptome profile in ovine peripheral blood mononuclear cells
por: Guo, Xiaofei, et al.
Publicado: (2020)

A globally occurring indel polymorphism in the promoter of the IFNA2 gene is not associated with severity of malaria but with the positivity rate of HCV
por: Tena-Tomás, Cristina, et al.
Publicado: (2008)

Influence of Single Deuterium Replacement on Frequency of Hydrogen Bond Dissociation in IFNA17 under the Highest Critical Energy Range
por: Basov, Alexander, et al.
Publicado: (2022)

Corrigendum: Elevated IFNA1 and suppressed IL12p40 associated with persistent hyperinflammation in COVID-19 pneumonia
por: Jeon, Kyeongseok, et al.
Publicado: (2023)

Effect of Interleukin-29 on Interferon-α Secretion by Peripheral Blood Mononuclear Cells
por: Cho, Chi Hyun, et al.
Publicado: (2015)

Beta3-Adrenoceptor Agonists: Possible Role in the Treatment of Overactive Bladder
por: Igawa, Yasuhiko, et al.
Publicado: (2010)

Modulation of TNF-α Secretion in Peripheral Blood Mononuclear Cells by Cocoa Flavanols and Procyanidins
por: Mao, T. K., et al.
Publicado: (2002)

Role for Lipids Secreted by Irradiated Peripheral Blood Mononuclear Cells in Inflammatory Resolution in Vitro
por: Panahipour, Layla, et al.
Publicado: (2020)

TLR-Mediated Cytokine Gene Expression in Chicken Peripheral Blood Mononuclear Cells as a Measure to Characterize Immunobiotics
por: Slawinska, Anna, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_i44d10i6g8a7un3e80c269smvn