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Motoneuron Differentiation of Induced Pluripotent Stem Cells from SOD1G93A Mice
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder mainly affecting motor neurons. Mutations in superoxide dismutase-1 (SOD-1) account for about 20% of familial ALS patients. A robust supply of motoneurons carrying the mutated gene would help understand the causes of motoneuron deat...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3665598/ https://www.ncbi.nlm.nih.gov/pubmed/23724084 http://dx.doi.org/10.1371/journal.pone.0064720 |