Long-Term Exposure to Cigarette Smoke Extract Induces Hypomethylation at the RUNX3 and IGF2-H19 Loci in Immortalized Human Urothelial Cells

Cigarette smoking is the single most important epidemiological risk factor for bladder cancer but it is not known whether exposure of urothelial cells to the systemic soluble contents of cigarette smoke is directly causative to bladder cancer and the associated epigenetic changes such as tumor suppr...

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Detalles Bibliográficos
Autores principales: Chen, Li-Mei, Nergard, Jennifer C., Ni, Liqiang, Rosser, Charles J., Chai, Karl X.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3665628/
https://www.ncbi.nlm.nih.gov/pubmed/23724145
http://dx.doi.org/10.1371/journal.pone.0065513

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3665628/
https://www.ncbi.nlm.nih.gov/pubmed/23724145
http://dx.doi.org/10.1371/journal.pone.0065513

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