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Evaluating glymphatic pathway function utilizing clinically relevant intrathecal infusion of CSF tracer

BACKGROUND: Neurodegenerative diseases such as Alzheimer’s are associated with the aggregation of endogenous peptides and proteins that contribute to neuronal dysfunction and loss. The glymphatic system, a brain-wide perivascular pathway along which cerebrospinal fluid (CSF) and interstitial fluid (...

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Detalles Bibliográficos
Autores principales: Yang, Lijun, Kress, Benjamin T, Weber, Harris J, Thiyagarajan, Meenakshisundaram, Wang, Baozhi, Deane, Rashid, Benveniste, Helene, Iliff, Jeffrey J, Nedergaard, Maiken
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3665671/
https://www.ncbi.nlm.nih.gov/pubmed/23635358
http://dx.doi.org/10.1186/1479-5876-11-107