Activation of Akt pathway by transcription-independent mechanisms of retinoic acid promotes survival and invasion in lung cancer cells

BACKGROUND: All-trans retinoic acid (ATRA) is currently being used in clinical trials for cancer treatment. The use of ATRA is limited because some cancers, such as lung cancer, show resistance to treatment. However, little is known about the molecular mechanisms that regulate resistance to ATRA tre...

Descripción completa

Detalles Bibliográficos
Autores principales: García-Regalado, Alejandro, Vargas, Miguel, García-Carrancá, Alejandro, Aréchaga-Ocampo, Elena, González-De la Rosa, Claudia Haydée
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3665688/
https://www.ncbi.nlm.nih.gov/pubmed/23693014
http://dx.doi.org/10.1186/1476-4598-12-44

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3665688/
https://www.ncbi.nlm.nih.gov/pubmed/23693014
http://dx.doi.org/10.1186/1476-4598-12-44

Ejemplares similares