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GABA progenitors grafted into the adult epileptic brain control seizures and abnormal behavior

Impaired GABA–mediated neurotransmission has been implicated in many neurologic diseases including epilepsy, intellectual disability, and psychiatric disorders. Here we report that inhibitory neuron transplantation into the hippocampus of adult mice with confirmed epilepsy at the time of grafting dr...

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Detalles Bibliográficos
Autores principales: Hunt, Robert F., Girskis, Kelly M., Rubenstein, John L., Alvarez–Buylla, Arturo, Baraban, Scott C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3665733/
https://www.ncbi.nlm.nih.gov/pubmed/23644485
http://dx.doi.org/10.1038/nn.3392