Cargando…
GABA progenitors grafted into the adult epileptic brain control seizures and abnormal behavior
Impaired GABA–mediated neurotransmission has been implicated in many neurologic diseases including epilepsy, intellectual disability, and psychiatric disorders. Here we report that inhibitory neuron transplantation into the hippocampus of adult mice with confirmed epilepsy at the time of grafting dr...
Autores principales: | Hunt, Robert F., Girskis, Kelly M., Rubenstein, John L., Alvarez–Buylla, Arturo, Baraban, Scott C. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3665733/ https://www.ncbi.nlm.nih.gov/pubmed/23644485 http://dx.doi.org/10.1038/nn.3392 |
Ejemplares similares
-
PAFAH1B1 haploinsufficiency disrupts GABA neurons and synaptic E/I balance in the dentate gyrus
por: Dinday, Matthew T., et al.
Publicado: (2017) -
Publisher Correction: PAFAH1B1 haploinsufficiency disrupts GABA neurons and synaptic E/I balance in the dentate gyrus
por: Dinday, Matthew T., et al.
Publicado: (2018) -
Encephalitis patient-derived monoclonal GABA(A) receptor antibodies cause epileptic seizures
por: Kreye, Jakob, et al.
Publicado: (2021) -
Human Fetal Brain-Derived Neural Stem/Progenitor Cells Grafted into the Adult Epileptic Brain Restrain Seizures in Rat Models of Temporal Lobe Epilepsy
por: Lee, Haejin, et al.
Publicado: (2014) -
Epileptic seizures
por: Anwar, Haleema, et al.
Publicado: (2020)