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Contactin-1 Reduces E-Cadherin Expression Via Activating AKT in Lung Cancer

Contactin-1 has been shown to promote cancer metastasis. However, the underlying mechanisms remain unclear. We report here that knockdown of contactin-1 in A549 lung cancer cells reduced A549 cell invasion and the cell's ability to grow in soft agar without affecting cell proliferation. Reducti...

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Detalles Bibliográficos
Autores principales: Yan, Judy, Wong, Nicholas, Hung, Claudia, Chen, Wendy Xin-Yi, Tang, Damu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3665745/
https://www.ncbi.nlm.nih.gov/pubmed/23724143
http://dx.doi.org/10.1371/journal.pone.0065463