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Contactin-1 Reduces E-Cadherin Expression Via Activating AKT in Lung Cancer
Contactin-1 has been shown to promote cancer metastasis. However, the underlying mechanisms remain unclear. We report here that knockdown of contactin-1 in A549 lung cancer cells reduced A549 cell invasion and the cell's ability to grow in soft agar without affecting cell proliferation. Reducti...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3665745/ https://www.ncbi.nlm.nih.gov/pubmed/23724143 http://dx.doi.org/10.1371/journal.pone.0065463 |