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Spatiotemporal Characterization of mTOR Kinase Activity Following Kainic Acid Induced Status Epilepticus and Analysis of Rat Brain Response to Chronic Rapamycin Treatment

Mammalian target of rapamycin (mTOR) is a protein kinase that senses nutrient availability, trophic factors support, cellular energy level, cellular stress, and neurotransmitters and adjusts cellular metabolism accordingly. Adequate mTOR activity is needed for development as well as proper physiolog...

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Detalles Bibliográficos
Autores principales: Macias, Matylda, Blazejczyk, Magdalena, Kazmierska, Paulina, Caban, Bartosz, Skalecka, Agnieszka, Tarkowski, Bartosz, Rodo, Anna, Konopacki, Jan, Jaworski, Jacek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3665782/
https://www.ncbi.nlm.nih.gov/pubmed/23724051
http://dx.doi.org/10.1371/journal.pone.0064455