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The Lantibiotic Peptide Labyrinthopeptin A1 Demonstrates Broad Anti-HIV and Anti-HSV Activity with Potential for Microbicidal Applications

Lantibiotics are peptides, produced by bacteria, that contain the noncanonical amino acid lanthionine and many of them exhibit antibacterial activities. The labyrinthopeptin A1 (LabyA1) is a prototype peptide of a novel class of carbacyclic lantibiotics. Here, we extensively evaluated its broad-spec...

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Detalles Bibliográficos
Autores principales: Férir, Geoffrey, Petrova, Mariya I., Andrei, Graciela, Huskens, Dana, Hoorelbeke, Bart, Snoeck, Robert, Vanderleyden, Jos, Balzarini, Jan, Bartoschek, Stefan, Brönstrup, Mark, Süssmuth, Roderich D., Schols, Dominique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3665789/
https://www.ncbi.nlm.nih.gov/pubmed/23724015
http://dx.doi.org/10.1371/journal.pone.0064010