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Crystal Structure of a Novel N-Substituted L-Amino Acid Dioxygenase from Burkholderia ambifaria AMMD

A novel dioxygenase from Burkholderia ambifaria AMMD (SadA) stereoselectively catalyzes the C3-hydroxylation of N-substituted branched-chain or aromatic L-amino acids, especially N-succinyl-L-leucine, coupled with the conversion of α-ketoglutarate to succinate and CO(2). To elucidate the structural...

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Detalles Bibliográficos
Autores principales: Qin, Hui-Min, Miyakawa, Takuya, Jia, Min Ze, Nakamura, Akira, Ohtsuka, Jun, Xue, You-Lin, Kawashima, Takashi, Kasahara, Takuya, Hibi, Makoto, Ogawa, Jun, Tanokura, Masaru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3665795/
https://www.ncbi.nlm.nih.gov/pubmed/23724013
http://dx.doi.org/10.1371/journal.pone.0063996