HDAC Up-Regulation in Early Colon Field Carcinogenesis Is Involved in Cell Tumorigenicity through Regulation of Chromatin Structure

Normal cell function is dependent on the proper maintenance of chromatin structure. Regulation of chromatin structure is controlled by histone modifications that directly influence chromatin architecture and genome function. Specifically, the histone deacetylase (HDAC) family of proteins modulate ch...

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Detalles Bibliográficos
Autores principales: Stypula-Cyrus, Yolanda, Damania, Dhwanil, Kunte, Dhananjay P., Cruz, Mart Dela, Subramanian, Hariharan, Roy, Hemant K., Backman, Vadim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3665824/
https://www.ncbi.nlm.nih.gov/pubmed/23724067
http://dx.doi.org/10.1371/journal.pone.0064600

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3665824/
https://www.ncbi.nlm.nih.gov/pubmed/23724067
http://dx.doi.org/10.1371/journal.pone.0064600

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