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Proteolytic Processing of Angiotensin-I in Human Blood Plasma

In mammalian species, except humans, N-terminal processing of the precursor peptide angiotensin I (ANG-1-10) into ANG-2-10 or ANG-3-10 was reported. Here we hypothesize that aminopeptidase-generated angiotensins bearing the same C-terminus as ANG-1-10 are also present in humans. We demonstrate the t...

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Detalles Bibliográficos
Autores principales: Hildebrand, Diana, Merkel, Philipp, Eggers, Lars Florian, Schlüter, Hartmut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3665828/
https://www.ncbi.nlm.nih.gov/pubmed/23724017
http://dx.doi.org/10.1371/journal.pone.0064027