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In Vitro and In Vivo Activities of Ruthenium(II) Phosphine/Diimine/Picolinate Complexes (SCAR) against Mycobacterium tuberculosis

Rifampicin, discovered more than 50 years ago, represents the last novel class of antibiotics introduced for the first-line treatment of tuberculosis. Drugs in this class form part of a 6-month regimen that is ineffective against MDR and XDR TB, and incompatible with many antiretroviral drugs. Inves...

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Detalles Bibliográficos
Autores principales: Pavan, Fernando R., Poelhsitz, Gustavo V., da Cunha, Lucas V. P., Barbosa, Marilia I. F., Leite, Sergio R. A., Batista, Alzir A., Cho, Sang H., Franzblau, Scott G., de Camargo, Mariana S., Resende, Flávia A., Varanda, Eliana A., Leite, Clarice Q. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3665843/
https://www.ncbi.nlm.nih.gov/pubmed/23724039
http://dx.doi.org/10.1371/journal.pone.0064242