Cargando…

In Vitro and In Vivo Activities of Ruthenium(II) Phosphine/Diimine/Picolinate Complexes (SCAR) against Mycobacterium tuberculosis

Rifampicin, discovered more than 50 years ago, represents the last novel class of antibiotics introduced for the first-line treatment of tuberculosis. Drugs in this class form part of a 6-month regimen that is ineffective against MDR and XDR TB, and incompatible with many antiretroviral drugs. Inves...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pavan, Fernando R., Poelhsitz, Gustavo V., da Cunha, Lucas V. P., Barbosa, Marilia I. F., Leite, Sergio R. A., Batista, Alzir A., Cho, Sang H., Franzblau, Scott G., de Camargo, Mariana S., Resende, Flávia A., Varanda, Eliana A., Leite, Clarice Q. F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3665843/ https://www.ncbi.nlm.nih.gov/pubmed/23724039 http://dx.doi.org/10.1371/journal.pone.0064242

Ejemplares similares

Development of Copper Complexes with Diimines and Dipicolinate as Anticancer Cytotoxic Agents
por: Alvarez, Natalia, et al.
Publicado: (2023)

Nanostructured Lipid Systems as a Strategy to Improve the in Vitro Cytotoxicity of Ruthenium(II) Compounds
por: de Freitas, Eduardo Sinesio, et al.
Publicado: (2014)

New Heteroleptic Ruthenium(II) Complexes with Sulfamethoxypyridazine and Diimines as Potential Antitumor Agents
por: de Melo, Ariane C.C., et al.
Publicado: (2019)

Synthesis, Characterization, Cytotoxic Activity, and Interactions with CT-DNA and BSA of Cationic Ruthenium(II) Complexes Containing Dppm and Quinoline Carboxylates
por: da Silva, Edinaldo N., et al.
Publicado: (2017)

Surface-Bound Ruthenium Diimine Organometallic Complexes: Excited-State Properties
por: Abbott, Geoffrey, et al.
Publicado: (2014)

Ruthenium Picolinate Complex as a Redox Photosensitizer With Wide-Band Absorption
por: Tamaki, Yusuke, et al.
Publicado: (2019)

Tris(aminomethyl)phosphines and Their Copper(I) (Pseudo)halide Complexes with Aromatic Diimines—A Critical Retrospection
por: Starosta, Radosław
Publicado: (2023)

Cationic ruthenium alkylidene catalysts bearing phosphine ligands
por: Endo, Koji, et al.
Publicado: (2016)

Latent ruthenium–indenylidene catalysts bearing a N-heterocyclic carbene and a bidentate picolinate ligand
por: Schmid, Thibault E, et al.
Publicado: (2015)

α-Diimine synthesis via titanium-mediated multicomponent diimination of alkynes with C-nitrosos
por: Frye, Connor W., et al.
Publicado: (2021)

A Novel Ruthenium(II) Complex With Lapachol Induces G2/M Phase Arrest Through Aurora-B Kinase Down-Regulation and ROS-Mediated Apoptosis in Human Prostate Adenocarcinoma Cells
por: De Grandis, Rone A., et al.
Publicado: (2021)

A Ruthenium(II) Complex Supported by Trithiacyclononane and Aromatic Diimine Ligand as Luminescent Switch-On Probe for Biomolecule Detection and Protein Staining
por: Wong, Chun-Yuen, et al.
Publicado: (2014)

Experimental and Computational Studies of Ruthenium Complexes Bearing Z-Acceptor Aluminum-Based Phosphine Pincer Ligands
por: Isaac, Connie J., et al.
Publicado: (2022)

3-Chloro-6-(3,5-dimethyl-1H-pyrazol-1-yl)picolinic acid–triphenylphosphine oxide (1/1)
por: Hu, Fei-Long, et al.
Publicado: (2008)

Camphor-based symmetric diimines as inhibitors of influenza virus reproduction
por: Sokolova, Anastasiya S., et al.
Publicado: (2014)

The Physiological Action of Picolinic Acid in the Human Brain
por: Grant, R.S., et al.
Publicado: (2009)

Synthesis of Symmetrical and Non-symmetrical Diimines from Dimedone
por: Saeed, Bahjat A., et al.
Publicado: (2009)

Tricarbonylbis(tricyclohexylphosphine-κP)ruthenium(0) toluene solvate
por: Nader, Andreas, et al.
Publicado: (2008)

Synthesis and Spectrosopic Identification of Hybrid 3-(Triethoxysilyl)propylamine Phosphine Ruthenium(II) Complexes
por: Warad, Ismail, et al.
Publicado: (2010)

Enantioselective intramolecular C–H amination of aliphatic azides by dual ruthenium and phosphine catalysis
por: Qin, Jie, et al.
Publicado: (2019)

α-Diimine Cisplatin Derivatives: Synthesis, Structure, Cyclic Voltammetry and Cytotoxicity
por: Yambulatov, Dmitriy S., et al.
Publicado: (2022)

Ruthenium Complexes Bearing α-Diimine Ligands and Their Catalytic Applications in N-Alkylation of Amines, α-Alkylation of Ketones, and β-Alkylation of Secondary Alcohols
por: Gayathri, Sekar, et al.
Publicado: (2022)

Ethyl {6-[6-(ethoxycarbonyl)picolinamidocarbonyl]picolinamidocarbonyl}picolinate
por: Li, Xiao, et al.
Publicado: (2008)

New phosphine-diamine and phosphine-amino-alcohol tridentate ligands for ruthenium catalysed enantioselective hydrogenation of ketones and a concise lactone synthesis enabled by asymmetric reduction of cyano-ketones
por: Fuentes, José A, et al.
Publicado: (2012)

Byrsonima fagifolia Niedenzu Apolar Compounds with Antitubercular Activity
por: Higuchi, C. T., et al.
Publicado: (2011)

Dichlorido(η(6)-toluene)[tris(4-methoxyphenyl)phosphine]ruthenium(II)
por: Wang, Lei, et al.
Publicado: (2008)

Pathways of ion–molecular interactions of nucleogenic phenyl cations with the nucleophilic centers of picolines
por: Shchepina, Nadezhda E, et al.
Publicado: (2012)

Chiral C(2)-Symmetric Diimines with 4,5-Diazafluorene Units
por: Vasilyev, Eugene S., et al.
Publicado: (2019)

Transfer of Sequence Information and Replication of Diimine Duplexes
por: Strom, Kyle R., et al.
Publicado: (2019)

Methyl 5-bromo-6-methylpicolinate
por: Wu, Ya-Ming, et al.
Publicado: (2008)

Chromophore-Functionalized Phenanthro-diimine Ligands and Their Re(I) Complexes
por: Kisel, Kristina S., et al.
Publicado: (2018)

Cytotoxicity and anti-tumor effects of new ruthenium complexes on triple negative breast cancer cells
por: Popolin, Cecília P., et al.
Publicado: (2017)

Characterization and Quantification of Compounds in the Hydroalcoholic Extract of the Leaves from Terminalia catappa Linn. (Combretaceae) and Their Mutagenic Activity
por: Mininel, Francisco José, et al.
Publicado: (2014)

Evaluation of Estrogenic Potential of Flavonoids Using a Recombinant Yeast Strain and MCF7/BUS Cell Proliferation Assay
por: Resende, Flávia A., et al.
Publicado: (2013)

A ruthenium-based 5-fluorouracil complex with enhanced cytotoxicity and apoptosis induction action in HCT116 cells
por: Silva, Valdenizia Rodrigues, et al.
Publicado: (2018)

(η(6)-p-Cymene)bis(trichloridostannyl)(triethoxyphosphine-κP)ruthenium(II)
por: Shapovalov, Sergey S., et al.
Publicado: (2009)

A Supramolecular Interaction of a Ruthenium Complex With Calf-Thymus DNA: A Ligand Binding Approach by NMR Spectroscopy
por: Kock, Flávio Vinícius Crizóstomo, et al.
Publicado: (2019)

A Nanostructured Lipid System to Improve the Oral Bioavailability of Ruthenium(II) Complexes for the Treatment of Infections Caused by Mycobacterium tuberculosis
por: da Silva, Patricia B., et al.
Publicado: (2018)

Silylation of Pyridine, Picolines, and Quinoline with a Zinc Catalyst
por: Prybil, Joshua W., et al.
Publicado: (2020)

Polymorphism in the 1/1 Pterostilbene/Picolinic Acid Cocrystal
por: Barbas, Rafael, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_bqsgf2hpghgbmfuleol9gpdlls