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Prime-Boost Strategies in Mucosal Immunization Affect Local IgA Production and the Type of Th Response

Combinations of different delivery routes for priming and boosting represent vaccination strategies that can modulate magnitude, quality, and localization of the immune response. A murine model was used to study T cell clonal expansion following intranasal (IN) or subcutaneous (SC) priming, and seco...

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Detalles Bibliográficos
Autores principales: Fiorino, Fabio, Pettini, Elena, Pozzi, Gianni, Medaglini, Donata, Ciabattini, Annalisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3665932/
https://www.ncbi.nlm.nih.gov/pubmed/23755051
http://dx.doi.org/10.3389/fimmu.2013.00128