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IRF4 Transcription Factor-Dependent CD11b(+) Dendritic Cells in Human and Mouse Control Mucosal IL-17 Cytokine Responses

Mouse and human dendritic cells (DCs) are composed of functionally specialized subsets, but precise interspecies correlation is currently incomplete. Here, we showed that murine lung and gut lamina propria CD11b(+) DC populations were comprised of two subsets: FLT3- and IRF4-dependent CD24(+)CD64(−)...

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Detalles Bibliográficos
Autores principales: Schlitzer, Andreas, McGovern, Naomi, Teo, Pearline, Zelante, Teresa, Atarashi, Koji, Low, Donovan, Ho, Adrian W.S., See, Peter, Shin, Amanda, Wasan, Pavandip Singh, Hoeffel, Guillaume, Malleret, Benoit, Heiseke, Alexander, Chew, Samantha, Jardine, Laura, Purvis, Harriet A., Hilkens, Catharien M.U., Tam, John, Poidinger, Michael, Stanley, E. Richard, Krug, Anne B., Renia, Laurent, Sivasankar, Baalasubramanian, Ng, Lai Guan, Collin, Matthew, Ricciardi-Castagnoli, Paola, Honda, Kenya, Haniffa, Muzlifah, Ginhoux, Florent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3666057/
https://www.ncbi.nlm.nih.gov/pubmed/23706669
http://dx.doi.org/10.1016/j.immuni.2013.04.011