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Evidence for a Role of LPGAT1 in Influencing BMI and Percent Body Fat in Native Americans

OBJECTIVE: A genome-wide association study (GWAS) was recently completed in 1120 Pima Indians to identify loci that influence BMI. Among the top 100 signals were three variants that mapped within the lysophosphatidylglycerol acyltransferase 1 (LPGAT1) gene. LPGAT1 belongs to a large family of acyltr...

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Detalles Bibliográficos
Autores principales: Traurig, Michael T, Orczewska, Julieanna I, Ortiz, Daniel J, Bian, Li, Marinelarena, Alejandra M, Kobes, Sayuko, Malhotra, Alka, Hanson, Robert L, Mason, Clint C, Knowler, William C, Bogardus, Clifton, Baier, Leslie J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3666094/
https://www.ncbi.nlm.nih.gov/pubmed/23505186
http://dx.doi.org/10.1002/oby.20243