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Hereditary Angioedema Therapy: Kallikrein Inhibition and Bradykinin Receptor Antagonism

Current strategies for the treatment of hereditary angioedema (HAE) include targeted inhibition or antagonism of the contact system, which is dysregulated in HAE patients by a C1 esterase inhibitor deficiency. Ecallantide, a plasma kallikrein inhibitor, and icatibant, a selective bradykinin-2 recept...

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Detalles Bibliográficos
Autor principal: Riedl, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: World Allergy Organization 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3666151/
https://www.ncbi.nlm.nih.gov/pubmed/23282868
http://dx.doi.org/10.1097/1939-4551-3-S3-S34