Insights into the Phosphoryl Transfer Catalyzed by cAMP-Dependent Protein Kinase: An X-ray Crystallographic Study of Complexes with Various Metals and Peptide Substrate SP20

[Image: see text] X-ray structures of several ternary substrate and product complexes of the catalytic subunit of cAMP-dependent protein kinase (PKAc) have been determined with different bound metal ions. In the PKAc complexes, Mg(2+), Ca(2+), Sr(2+), and Ba(2+) metal ions could bind to the active s...

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Detalles Bibliográficos
Autores principales: Gerlits, Oksana, Waltman, Mary Jo, Taylor, Susan, Langan, Paul, Kovalevsky, Andrey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2013
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3666212/
https://www.ncbi.nlm.nih.gov/pubmed/23672593
http://dx.doi.org/10.1021/bi400066a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3666212/
https://www.ncbi.nlm.nih.gov/pubmed/23672593
http://dx.doi.org/10.1021/bi400066a

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