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Insights into the Phosphoryl Transfer Catalyzed by cAMP-Dependent Protein Kinase: An X-ray Crystallographic Study of Complexes with Various Metals and Peptide Substrate SP20
[Image: see text] X-ray structures of several ternary substrate and product complexes of the catalytic subunit of cAMP-dependent protein kinase (PKAc) have been determined with different bound metal ions. In the PKAc complexes, Mg(2+), Ca(2+), Sr(2+), and Ba(2+) metal ions could bind to the active s...
Autores principales: | Gerlits, Oksana, Waltman, Mary Jo, Taylor, Susan, Langan, Paul, Kovalevsky, Andrey |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2013
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3666212/ https://www.ncbi.nlm.nih.gov/pubmed/23672593 http://dx.doi.org/10.1021/bi400066a |
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