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Human Skin Keratinocytes Can Be Reprogrammed to Express Neuronal Genes and Proteins After a Single Treatment with Decitabine

Patient-specific cell replacement therapy is fast becoming the future of medicine, requiring safe, effective methods for reprogramming a patient's own cells. Previously, we showed that a single transient transfection with a plasmid encoding Oct4 was sufficient to reprogram human skin keratinocy...

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Detalles Bibliográficos
Autores principales: Bickenbach, Jackie R., Tomanek-Chalkley, Ann, Wiechert, Susan, Winter, Michael C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3666219/
https://www.ncbi.nlm.nih.gov/pubmed/23741634
http://dx.doi.org/10.1089/biores.2012.0298