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Impact of macromolecular crowding on DNA replication

Enzymatic activities in vivo occur in a crowded environment composed of many macromolecules. This environment influences DNA replication by increasing the concentration of the constituents, desolvation, decreasing the degrees of freedom for diffusion and hopping of proteins onto DNA, and enhancing b...

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Detalles Bibliográficos
Autores principales: Akabayov, Barak, Akabayov, Sabine R., Lee, Seung–Joo, Wagner, Gerhard, Richardson, Charles C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3666333/
https://www.ncbi.nlm.nih.gov/pubmed/23511479
http://dx.doi.org/10.1038/ncomms2620