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α-Synuclein Modification in an ALS Animal Model

Amyotrophic lateral sclerosis (ALS) is a progressively paralytic neurodegenerative disease that can be caused by mutations in Cu/Zn-superoxide dismutase 1 (SOD1). Transgenic mice that overexpress mutant SOD1 develop paralysis and accumulate aggregates of mutant protein in the brainstem and spinal co...

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Detalles Bibliográficos
Autores principales: Yang, Eun Jin, Choi, Sun-Mi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3666397/
https://www.ncbi.nlm.nih.gov/pubmed/23762114
http://dx.doi.org/10.1155/2013/259381