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Nanoemulsion loaded with lycobetaine–oleic acid ionic complex: physicochemical characteristics, in vitro, in vivo evaluation, and antitumor activity

BACKGROUND: Intravenous injection of lycobetaine was found to show significant cytotoxic activity against (inter alia) Lewis lung carcinoma, but its therapeutic use is largely limited due to an extremely short half-life in blood. This study aimed at developing a novel lipid nanocarrier-based formula...

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Detalles Bibliográficos
Autores principales: Zhao, Hui, Lu, Hua, Gong, Tao, Zhang, Zhirong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3666662/
https://www.ncbi.nlm.nih.gov/pubmed/23723698
http://dx.doi.org/10.2147/IJN.S43892