Cargando…

Nanoemulsion loaded with lycobetaine–oleic acid ionic complex: physicochemical characteristics, in vitro, in vivo evaluation, and antitumor activity

BACKGROUND: Intravenous injection of lycobetaine was found to show significant cytotoxic activity against (inter alia) Lewis lung carcinoma, but its therapeutic use is largely limited due to an extremely short half-life in blood. This study aimed at developing a novel lipid nanocarrier-based formula...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhao, Hui, Lu, Hua, Gong, Tao, Zhang, Zhirong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2013
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3666662/ https://www.ncbi.nlm.nih.gov/pubmed/23723698 http://dx.doi.org/10.2147/IJN.S43892

Ejemplares similares

Mannosylated Lipid Nano-emulsions Loaded with Lycorine-oleic Acid Ionic Complex for Tumor Cell-specific Delivery
por: Guo, Yangming, et al.
Publicado: (2012)

A novel submicron emulsion system loaded with vincristine–oleic acid ion-pair complex with improved anticancer effect: in vitro and in vivo studies
por: Zhang, Ting, et al.
Publicado: (2013)

Ionically Crosslinked Complex Gels Loaded with Oleic Acid-Containing Vesicles for Transdermal Drug Delivery
por: Lai, Wing-Fu, et al.
Publicado: (2020)

Nanoemulsions of Hydroxysafflor Yellow A for Enhancing Physicochemical and In Vivo Performance
por: Zhang, Yingjie, et al.
Publicado: (2023)

Lycobetaine acts as a selective topoisomerase IIβ poison and inhibits the growth of human tumour cells
por: Barthelmes, H U, et al.
Publicado: (2001)

Preparation and in vitro and in vivo Study of Asiaticoside-Loaded Nanoemulsions and Nanoemulsions-Based Gels for Transdermal Delivery
por: Li, Huimin, et al.
Publicado: (2020)

Honokiol-Loaded Nanoemulsion for Glioblastoma Treatment: Statistical Optimization, Physicochemical Characterization, and an In Vitro Toxicity Assay
por: Gostyńska, Aleksandra, et al.
Publicado: (2023)

Rapamycin-Loaded, Capryol(TM) 90 and Oleic Acid Mediated Nanoemulsions: Formulation Development, Characterization and Toxicity Assessment
por: Sobhani, Hamideh, et al.
Publicado: (2018)

Comparison of Different Protein Emulsifiers on Physicochemical Properties of β-Carotene-Loaded Nanoemulsion: Effect on Formation, Stability, and In Vitro Digestion
por: Liu, Yanlong, et al.
Publicado: (2021)

Enhanced antitumor efficacy of lapachol-loaded nanoemulsion in breast cancer tumor model
por: Mendes Miranda, Sued Eustáquio, et al.
Publicado: (2021)

Preparation and in vitro and in vivo evaluation of an isoliquiritigenin-loaded ophthalmic nanoemulsion for the treatment of corneal neovascularization
por: Zhang, Rui, et al.
Publicado: (2022)

Ketoconazole-Loaded Cationic Nanoemulsion: In Vitro–Ex Vivo–In Vivo Evaluations to Control Cutaneous Fungal Infections
por: Shahid, Mudassar, et al.
Publicado: (2022)

Preparation and In Vivo Evaluation of Indomethacin Loaded True Nanoemulsions
por: Shakeel, Faiyaz, et al.
Publicado: (2010)

Design and evaluation of Lumefantrine – Oleic acid self nanoemulsifying ionic complex for enhanced dissolution
por: Patel, Ketan, et al.
Publicado: (2013)

The Impact of the Oil Phase Selection on Physicochemical Properties, Long-Term Stability, In Vitro Performance and Injectability of Curcumin-Loaded PEGylated Nanoemulsions
por: Đoković, Jelena B., et al.
Publicado: (2022)

Preparation and characteristics of lipid nanoemulsion formulations loaded with doxorubicin
por: Jiang, Sai-Ping, et al.
Publicado: (2013)

In vitro and in vivo Effects of Free and Chalcones-Loaded Nanoemulsions: Insights and Challenges in Targeted Cancer Chemotherapies
por: Winter, Evelyn, et al.
Publicado: (2014)

Development and Evaluations of Transdermally Delivered Luteolin Loaded Cationic Nanoemulsion: In Vitro and Ex Vivo Evaluations
por: Altamimi, Mohammad A., et al.
Publicado: (2021)

Formulation of Piperine-Loaded Nanoemulsion: In Vitro Characterization, Ex Vivo Evaluation, and Cell Viability Assessment
por: Alshehri, Sultan, et al.
Publicado: (2023)

Curcumin and Quercetin-Loaded Nanoemulsions: Physicochemical Compatibility Study and Validation of a Simultaneous Quantification Method
por: Vaz, Gustavo Richter, et al.
Publicado: (2020)

Crisaborole Loaded Nanoemulsion Based Chitosan Gel: Formulation, Physicochemical Characterization and Wound Healing Studies
por: Ansari, Mohd Nazam, et al.
Publicado: (2022)

Impact of high hydrostatic pressure on the micellar structures and physicochemical stability of casein nanoemulsion loading quercetin
por: Mao, Mengqi, et al.
Publicado: (2022)

The garlic extract‐loaded nanoemulsion: Study of physicochemical, rheological, and antimicrobial properties and its application in mayonnaise
por: Hassanzadeh, Hamed, et al.
Publicado: (2023)

Physicochemical Properties and Storage Stability of Food Protein-Stabilized Nanoemulsions
por: Li, Yangyang, et al.
Publicado: (2018)

Silver Nanocolloids Loaded with Betulinic Acid with Enhanced Antitumor Potential: Physicochemical Characterization and In Vitro Evaluation
por: Pinzaru, Iulia, et al.
Publicado: (2021)

Development of triptolide-nanoemulsion gels for percutaneous administration: physicochemical, transport, pharmacokinetic and pharmacodynamic characteristics
por: Yang, Meng, et al.
Publicado: (2017)

In vitro and in vivo antitumor effects of lupeol-loaded galactosylated liposomes
por: Zhang, Jun, et al.
Publicado: (2021)

Formulation Development and In Vitro/In Vivo Characterization of Methotrexate-Loaded Nanoemulsion Gel Formulations for Enhanced Topical Delivery
por: Latif, Muhammad Shahid, et al.
Publicado: (2022)

Physicochemical data of oleic acid-poloxamer organogel for intravaginal voriconazole delivery
por: Querobino, Samyr M., et al.
Publicado: (2019)

The liquid-glass-jamming transition in disordered ionic nanoemulsions
por: Braibanti, Marco, et al.
Publicado: (2017)

Peanut Coffee: Enhancement of Nutritional, Physicochemical, and Sensory Characteristics in Coffee Brewed with Conventional and High-Oleic Peanut Extracts
por: Lee, Jookyeong, et al.
Publicado: (2020)

Design and dermatokinetic appraisal of lornoxicam-loaded ultrafine self-nanoemulsion hydrogel for the management of inflammation: In vitro and in vivo studies
por: Al-Suwayeh, Saleh A., et al.
Publicado: (2023)

Development and Characterization of a Hydrogel Containing Curcumin-Loaded Nanoemulsion for Enhanced In Vitro Antibacteria and In Vivo Wound Healing
por: Le, Thi Thanh Ngoc, et al.
Publicado: (2023)

Phospholipid complex based nanoemulsion system for oral insulin delivery: preparation, in vitro, and in vivo evaluations
por: Hu, Xiong-Bin, et al.
Publicado: (2019)

Interaction of Lactoferrin with Unsaturated Fatty Acids: In Vitro and In Vivo Study of Human Lactoferrin/Oleic Acid Complex Cytotoxicity
por: Elizarova, Anna, et al.
Publicado: (2021)

Minoxidil Skin Delivery from Nanoemulsion Formulations Containing Eucalyptol or Oleic Acid: Enhanced Diffusivity and Follicular Targeting
por: Abd, Eman, et al.
Publicado: (2018)

In vitro and in vivo antitumor potential of carvacrol nanoemulsion against human lung adenocarcinoma A549 cells via mitochondrial mediated apoptosis
por: Khan, Imran, et al.
Publicado: (2018)

Evaluation of the Physicochemical and Antimicrobial Properties of Nanoemulsion-Based Polyherbal Mouthwash
por: Haq, Nazrul, et al.
Publicado: (2023)

Nanoemulsions as novel nanocarrieres for drug delivery across the skin: In-vitro, in-vivo evaluation of miconazole nanoemulsions for treatment of Candidiasis albicans
por: Farooq, Umar, et al.
Publicado: (2021)

Resveratrol-Loaded Nanoemulsions: In Vitro Activity on Human T24 Bladder Cancer Cells
por: Rinaldi, Federica, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_a25mkiur3rkk531eco4sqf1qi1