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Development and characterization of chitosan-PEG-TAT nanoparticles for the intracellular delivery of siRNA

Recently, cell-penetrating peptides have been proposed to translocate antibodies, proteins, and other molecules in targeted drug delivery. The proposed study presents the synthesis and characterization of a peptide-based chitosan nanoparticle for small interfering RNA (siRNA) delivery, in-vitro. Spe...

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Detalles Bibliográficos
Autores principales: Malhotra, Meenakshi, Tomaro-Duchesneau, Catherine, Saha, Shyamali, Kahouli, Imen, Prakash, Satya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3666663/
https://www.ncbi.nlm.nih.gov/pubmed/23723699
http://dx.doi.org/10.2147/IJN.S43683