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Insights on Cytochrome P450 Enzymes and Inhibitors Obtained Through QSAR Studies

The cytochrome P450 (CYP) superfamily of heme enzymes play an important role in the metabolism of a large number of endogenous and exogenous compounds, including most of the drugs currently on the market. Inhibitors of CYP enzymes have important roles in the treatment of several disease conditions s...

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Detalles Bibliográficos
Autores principales: Sridhar, Jayalakshmi, Liu, Jiawang, Foroozesh, Maryam, Klein Stevens, Cheryl L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3666846/
https://www.ncbi.nlm.nih.gov/pubmed/22864238
http://dx.doi.org/10.3390/molecules17089283