Trip12, a HECT domain E3 ubiquitin ligase, targets Sox6 for proteasomal degradation and affects fiber type-specific gene expression in muscle cells

BACKGROUND: A sophisticated level of coordinated gene expression is necessary for skeletal muscle fibers to obtain their unique functional identities. We have previously shown that the transcription factor Sox6 plays an essential role in coordinating muscle fiber type differentiation by acting as a...

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Detalles Bibliográficos
Autores principales: An, Chung-Il, Ganio, Edward, Hagiwara, Nobuko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3666947/
https://www.ncbi.nlm.nih.gov/pubmed/23663701
http://dx.doi.org/10.1186/2044-5040-3-11

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3666947/
https://www.ncbi.nlm.nih.gov/pubmed/23663701
http://dx.doi.org/10.1186/2044-5040-3-11

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