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Comparison of endogenous and overexpressed MyoD shows enhanced binding of physiologically bound sites
BACKGROUND: Transcription factor overexpression is common in biological experiments and transcription factor amplification is associated with many cancers, yet few studies have directly compared the DNA-binding profiles of endogenous versus overexpressed transcription factors. METHODS: We analyzed M...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3666993/ https://www.ncbi.nlm.nih.gov/pubmed/23566431 http://dx.doi.org/10.1186/2044-5040-3-8 |