AT1-receptor-deficiency induced atheroprotection in diabetic mice is partially mediated via PPARγ

OBJECTIVE: Peroxisome-proliferator–activated-receptor-γ (PPARγ) acts as a transcriptional regulator of multiple genes involved in glucose and lipid metabolism. In vitro studies showed that activated PPARγ suppresses AT1R-gene expression and vice versa. However, it has not yet been determined in vivo...

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Detalles Bibliográficos
Autores principales: Tiyerili, Vedat, Becher, Ulrich M, Aksoy, Adem, Lütjohann, Dieter, Wassmann, Sven, Nickenig, Georg, Mueller, Cornelius FH
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3667017/
https://www.ncbi.nlm.nih.gov/pubmed/23374104
http://dx.doi.org/10.1186/1475-2840-12-30

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3667017/
https://www.ncbi.nlm.nih.gov/pubmed/23374104
http://dx.doi.org/10.1186/1475-2840-12-30

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