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TLR4 Ligand/H(2)O(2) Enhances TGF-β1 Signaling to Induce Metastatic Potential of Non-Invasive Breast Cancer Cells by Activating Non-Smad Pathways

TGF-β1 has the potential to activate multiple signaling pathways required for inducing metastatic potential of tumor cells. However, TGF-β1 was inefficient in inducing metastatic potential of many non-invasive human tumor cells. Here we report that the enhancement of TGF-β1 signaling is required for...

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Detalles Bibliográficos
Autores principales: Zhou, Yuan-Hong, Liao, Sheng-Jun, Li, Dong, Luo, Jing, Wei, Jing-Jing, Yan, Bin, Sun, Rui, Shu, Yu, Wang, Qi, Zhang, Gui-Mei, Feng, Zuo-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3667026/
https://www.ncbi.nlm.nih.gov/pubmed/23734265
http://dx.doi.org/10.1371/journal.pone.0065906