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To Clone or Not to Clone? Induced Pluripotent Stem Cells Can Be Generated in Bulk Culture

Induced pluripotent stem cells (iPSCs) are usually clonally derived. The selection of fully reprogrammed cells generally involves picking of individual colonies with morphology similar to embryonic stem cells (ESCs). Given that fully reprogrammed cells are highly proliferative and escape from cellul...

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Detalles Bibliográficos
Autores principales: Willmann, Charlotte A., Hemeda, Hatim, Pieper, Lisa A., Lenz, Michael, Qin, Jie, Joussen, Sylvia, Sontag, Stephanie, Wanek, Paul, Denecke, Bernd, Schüler, Herdit M., Zenke, Martin, Wagner, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3667031/
https://www.ncbi.nlm.nih.gov/pubmed/23734247
http://dx.doi.org/10.1371/journal.pone.0065324