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To Clone or Not to Clone? Induced Pluripotent Stem Cells Can Be Generated in Bulk Culture
Induced pluripotent stem cells (iPSCs) are usually clonally derived. The selection of fully reprogrammed cells generally involves picking of individual colonies with morphology similar to embryonic stem cells (ESCs). Given that fully reprogrammed cells are highly proliferative and escape from cellul...
| Autores principales: | , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3667031/ https://www.ncbi.nlm.nih.gov/pubmed/23734247 http://dx.doi.org/10.1371/journal.pone.0065324 |