High Efficiency In Vivo Genome Engineering with a Simplified 15-RVD GoldyTALEN Design

Transcription activator-like effector nucleases (TALENs) enable genome engineering in cell culture and many organisms. Recently, the GoldyTALEN scaffold was shown to readily introduce mutations in zebrafish (Danio rerio) and livestock through non-homologous end joining (NHEJ) and homology-directed r...

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Detalles Bibliográficos
Autores principales: Ma, Alvin C., Lee, Han B., Clark, Karl J., Ekker, Stephen C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3667041/
https://www.ncbi.nlm.nih.gov/pubmed/23734242
http://dx.doi.org/10.1371/journal.pone.0065259

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3667041/
https://www.ncbi.nlm.nih.gov/pubmed/23734242
http://dx.doi.org/10.1371/journal.pone.0065259

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