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High Efficiency In Vivo Genome Engineering with a Simplified 15-RVD GoldyTALEN Design
Transcription activator-like effector nucleases (TALENs) enable genome engineering in cell culture and many organisms. Recently, the GoldyTALEN scaffold was shown to readily introduce mutations in zebrafish (Danio rerio) and livestock through non-homologous end joining (NHEJ) and homology-directed r...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3667041/ https://www.ncbi.nlm.nih.gov/pubmed/23734242 http://dx.doi.org/10.1371/journal.pone.0065259 |