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Electrostatic Mis-Interactions Cause Overexpression Toxicity of Proteins in E. coli
A majority of E. coli proteins when overexpressed inhibit its growth, but the reasons behind overexpression toxicity of proteins remain unknown. Understanding the mechanism of overexpression toxicity is important from evolutionary, biotechnological and possibly clinical perspectives. Here we study s...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3667126/ https://www.ncbi.nlm.nih.gov/pubmed/23734225 http://dx.doi.org/10.1371/journal.pone.0064893 |