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Electrostatic Mis-Interactions Cause Overexpression Toxicity of Proteins in E. coli

A majority of E. coli proteins when overexpressed inhibit its growth, but the reasons behind overexpression toxicity of proteins remain unknown. Understanding the mechanism of overexpression toxicity is important from evolutionary, biotechnological and possibly clinical perspectives. Here we study s...

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Detalles Bibliográficos
Autores principales: Singh, Gajinder Pal, Dash, Debasis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3667126/
https://www.ncbi.nlm.nih.gov/pubmed/23734225
http://dx.doi.org/10.1371/journal.pone.0064893