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Rac1 Selective Activation Improves Retina Ganglion Cell Survival and Regeneration

In adult mammals, after optic nerve injury, retinal ganglion cells (RGCs) do not regenerate their axons and most of them die by apoptosis within a few days. Recently, several strategies that activate neuronal intracellular pathways were proposed to prevent such degenerative processes. The rho-relate...

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Detalles Bibliográficos
Autores principales: Lorenzetto, Erika, Ettorre, Michele, Pontelli, Valeria, Bolomini-Vittori, Matteo, Bolognin, Silvia, Zorzan, Simone, Laudanna, Carlo, Buffelli, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3667179/
https://www.ncbi.nlm.nih.gov/pubmed/23734197
http://dx.doi.org/10.1371/journal.pone.0064350