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Clostridium perfringens Beta-Toxin Induces Necrostatin-Inhibitable, Calpain-Dependent Necrosis in Primary Porcine Endothelial Cells

Clostridium perfringens β-toxin (CPB) is a β-barrel pore-forming toxin and an essential virulence factor of C. perfringens type C strains, which cause fatal hemorrhagic enteritis in animals and humans. We have previously shown that CPB is bound to endothelial cells within the intestine of affected p...

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Detalles Bibliográficos
Autores principales: Autheman, Delphine, Wyder, Marianne, Popoff, Michel, D’Herde, Katharina, Christen, Stephan, Posthaus, Horst
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3667183/
https://www.ncbi.nlm.nih.gov/pubmed/23734212
http://dx.doi.org/10.1371/journal.pone.0064644