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Perilipin-Mediated Lipid Droplet Formation in Adipocytes Promotes Sterol Regulatory Element-Binding Protein-1 Processing and Triacylglyceride Accumulation

Sterol regulatory element-binding protein-1 (SREBP-1) has been thought to be a critical factor that assists adipogenesis. During adipogenesis SREBP-1 stimulates lipogenic gene expression, and peroxisome proliferator-activated receptor γ (PPARγ) enhances perilipin (plin) gene expression, resulting in...

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Detalles Bibliográficos
Autores principales: Takahashi, Yu, Shinoda, Akihiro, Furuya, Norihiko, Harada, Eri, Arimura, Naoto, Ichi, Ikuyo, Fujiwara, Yoko, Inoue, Jun, Sato, Ryuichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3667186/
https://www.ncbi.nlm.nih.gov/pubmed/23734208
http://dx.doi.org/10.1371/journal.pone.0064605