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Dysregulated Proinflammatory and Fibrogenic Phenotype of Fibroblasts in Cystic Fibrosis

Morbi-mortality in cystic fibrosis (CF) is mainly related to chronic lung infection and inflammation, uncontrolled tissue rearrangements and fibrosis, and yet the underlying mechanisms remain largely unknown. We evaluated inflammatory and fibrosis responses to bleomycin in F508del homozygous and wil...

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Detalles Bibliográficos
Autores principales: Huaux, François, Noel, Sabrina, Dhooghe, Barbara, Panin, Nadtha, Lo Re, Sandra, Lison, Dominique, Wallemacq, Pierre, Marbaix, Etienne, Scholte, Bob J., Lebecque, Patrick, Leal, Teresinha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3667188/
https://www.ncbi.nlm.nih.gov/pubmed/23734196
http://dx.doi.org/10.1371/journal.pone.0064341