Testosterone-derived estradiol production by male endothelium is robust and dependent on p450 aromatase via estrogen receptor alpha

Vascular endothelium expresses both the estrogen receptors (ERs) α and β, and ERα mediates development of early atherosclerosis in male mice. This process is thought to be testosterone-dependent. We hypothesized that male murine aortic endothelium produces robust levels of estradiol by aromatase con...

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Detalles Bibliográficos
Autores principales: Villablanca, Amparo C, Tetali, Sarada, Altman, Robin, Ng, Kenneth F, Rutledge, John C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3667361/
https://www.ncbi.nlm.nih.gov/pubmed/23741647
http://dx.doi.org/10.1186/2193-1801-2-214

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3667361/
https://www.ncbi.nlm.nih.gov/pubmed/23741647
http://dx.doi.org/10.1186/2193-1801-2-214

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